Dr. Audrey Lim, Dr. Shaun Murphy and Dr. Morgan Reznick treat a 25-year-old runner suffering from severe swelling; but when things take a turn for the worse, Dr. Shaun Murphy enlists the help of Dr. Carly Lever. Meanwhile, Dr. Alex Park, Dr. Claire Browne and Dr. Neil Melendez treat two 16-year-old cancer patients who are dating; and Dr. Shaun Murphy and Dr. Carly Lever work toward intimacy.