Alexander and Cesare are reconciled at last. The Papal Armies have been fortified with the money saved from the Crusade and the proceeds of the Jubilee. Cesare marches his fearsome army to finish what Juan started – lay siege to Forli. Micheletto reappears. Following a scuffle with Cesare, a drunken Alfonso is near death and Lucrezia turns to her potions to end his life painlessly. Cesare vows that Lucrezia will now be his for good.